The quarterfinals of the 2021 League of Legends Championship Series Lock In knockout stage has concluded and the semifinals matches have subsequently been set. The first quarterfinal match was between 100 Thieves and Immortals. Despite an admirable performance for the IMT Academy roster — particularly from jungler Nicholas James Joseph "Potluck" Pollock — 100 swept the best-of-three series and moved on to the semifinals. 

Cloud9 took on TSM next, which was a far more contentious series. However, the primary difference in C9's 2-1 win was in the bot lane, where Jesper "Zven" Svenningsen and Philippe "Vulcan" Laflamme absolutely shellacked Lawrence "Lost" Hui and Hu "SwordArt" Shuo-Chieh. Vulcan was awarded Mastercard Nexus Player of the Week for his performance due to his level of play with his AD Carry as well as his stellar coordination with Cloud9 jungler Robert "Blaber" Huang.

Golden Guardians faced off against Evil Geniuses with GG mid laner Nicholas "Ablazeolive" Abbott just barely making the start after a resolution of temporary health issues. EG top laner Jeong "Impact" Eon-young continued the immaculate Renekton play he's showcased throughout the young season, but EG fumbled his lead with an imperfect dive and Rift Herald usage. Still, EG managed to close out game 1 and then, in a more decisive fashion, game 2 and the series.

The last series featured Team Liquid jungler Lucas "Santorin" Larsen facing off against his old team, FlyQuest. Both Santorin and FLY jungler Brandon Joel "Josedeodo" Villegas missed the first week of the LCS Lock In due to visa issues, and while the jungle matchup was relatively close, the differential between other players on Team Liquid and FlyQuest earned TL a 2-0 victory and a ticket to the semifinals. 

100 Thieves will face off against Cloud9 in a best-of-five series and Evil Geniuses will take on Team Liquid on the other side of the bracket. Both semifinals will take place on Saturday, Jan 30, and the two winners will play each other in the best-of-five finals on Sunday, January 31.

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